Association of Albumin-Corrected Serum Calcium Levels with Colorectal Cancer Survival Outcomes.

ABSTRACT: In epidemiological studies, higher calcium intake has been associated with decreased colorectal cancer (CRC) incidence. However, whether circulating calcium concentrations are associated with CRC prognosis is largely unknown. In this retrospective cohort analysis, we identified 498 patients diagnosed with stage I-IV CRC between the years of 2000 and 2018 in whom calcium and albumin level measurements within 3 months of diagnosis had been taken. We used the Kaplan-Meier method for survival analysis. We used multivariate Cox proportional hazards regression to identify associations between corrected calcium levels and CRC survival outcomes. Corrected calcium levels in the highest tertile were associated with significantly lower progression-free survival rates (hazard ratio (HR) 1.85; 95% conf

SUBMITTER: Silveira MN 

PROVIDER: S-EPMC9144533 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature