Ontology highlight
ABSTRACT:
SUBMITTER: Ampong I
PROVIDER: S-EPMC9144635 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Ampong Isaac I Zimmerman Kip D KD Nathanielsz Peter W PW Cox Laura A LA Olivier Michael M
Metabolites 20220511 5
Gas chromatography-coupled mass spectrometry (GC-MS) has been used in biomedical research to analyze volatile, non-polar, and polar metabolites in a wide array of sample types. Despite advances in technology, missing values are still common in metabolomics datasets and must be properly handled. We evaluated the performance of ten commonly used missing value imputation methods with metabolites analyzed on an HR GC-MS instrument. By introducing missing values into the complete (i.e., data without ...[more]