Diversity of Cytochrome c Oxidase Assembly Proteins in Bacteria.

ABSTRACT: Cytochrome c oxidase in animals, plants and many aerobic bacteria functions as the terminal enzyme of the respiratory chain where it reduces molecular oxygen to form water in a reaction coupled to energy conservation. The three-subunit core of the enzyme is conserved, whereas several proteins identified to function in the biosynthesis of the common family A1 cytochrome c oxidase show diversity in bacteria. Using the model organisms Bacillus subtilis, Corynebacterium glutamicum, Paracoccus denitrificans, and Rhodobacter sphaeroides, the present review focuses on proteins for assembly of the heme a, heme a₃, Cu_B, and Cu_A metal centers. The known biosynthesis proteins are, in most cases, discovered throug

SUBMITTER: Hederstedt L 

PROVIDER: S-EPMC9145763 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature