Epiphenomenal Re-Entry and Spurious Focal Activation Detection by Atrial Fibrillation Mapping Algorithms.

ABSTRACT:

Objectives

The purpose of this study was to validate the ability of mapping algorithms to detect rotational activations (RoA) and focal activations (FoA) during fibrillatory conduction (FC) and atrial fibrillation (AF) and understand their mechanistic relevance.

Background

Mapping algorithms have been proposed to detect RoA and FoA to guide AF ablation.

Methods

Rapid left atrial pacing created FC-fibrillatory electrograms-with and without AF induction in dogs (n = 17). Activation maps were constructed using Topera (Abbott, St. Paul, Minnesota) or CARTOFINDER (Biosense Webster, Irvine, California) algorithms. Mapping strategies included: panoramic noncontact mapping with a basket catheter (CARTOFINDER n = 6, Topera n = 5); and sequential contact mapping using 8-spline

SUBMITTER: Hemam ME 

PROVIDER: S-EPMC9146411 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature