Dry Eye Parameters and Lid Geometry in Adults Born Extremely, Very, and Moderately Preterm with and without ROP: Results from the Gutenberg Prematurity Eye Study.

ABSTRACT:

Background/aims

This study aimed to analyze the effects of perinatal history on tear film properties and lid geometry in adults born preterm.

Methods

The Gutenberg Prematurity Eye Study (GPES) is a German prospective examination of adults born preterm and term aged 18 to 52 years with Keratograph^® 5M and Schirmer test I. Main outcome measures were first non-invasive tear film break-up time (F-NITBUT), bulbar redness (BR), Schirmer test, and nasal palpebral angle measurement. The associations with gestational age (GA), birth weight (BW), and BW percentile, retinopathy of prematurity (ROP), ROP treatment, and other perinatal factors were evaluated using regression analyses.

Results

489 eyes of 255 preterm and 277 eyes of 139 full-term individuals (aged 28.6 +

SUBMITTER: Fieß A 

PROVIDER: S-EPMC9147172 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature