A Systematic Review and a Meta-Analysis of the Yellow Fever Vaccine in the Elderly Population.

ABSTRACT: We conducted a systematic review and a meta-analysis to assess the risk of serious adverse events in the elderly after yellow fever vaccination compared to the non-elderly population. We searched multiple databases and grey literature, and we selected research without language and publication date restrictions. Studies were analyzed in a descriptive way and meta-analyzed and expressed in terms of prevalence ratio and risk ratio with a 95% confidence interval, depending on the degree of heterogeneity found. A total of 18 studies were included and 11 were meta-analyzed. The results obtained through the meta-analysis showed a risk of serious adverse events after yellow fever vaccination three times higher for the elderly when compared to the non-elderly population and five times higher for pe

SUBMITTER: de Abreu AJL 

PROVIDER: S-EPMC9147422 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature