Blood Pressure Increase following COVID-19 Vaccination: A Systematic Overview and Meta-Analysis.

ABSTRACT: Coronavirus disease 2019 (COVID-19) vaccines proved a strong clinical efficacy against symptomatic or moderate/severe COVID-19 and are considered the most promising approach for curbing the pandemic. However, some questions regarding the safety of COVID-19 vaccines have been recently raised. Among adverse events to vaccines and despite a lack of signal during phase III clinical trials, an increase in blood pressure (BP) after COVID-19 vaccination has been reported as a potential adverse reaction. We systematically analyze this topic and undertook a meta-analysis of available data to estimate the proportion of patients with abnormal BP or raise in BP after vaccination. Six studies entered the final analysis. Overall, studies accrued 357,387 subjects with 13,444 events of abnormal or increas

SUBMITTER: Angeli F 

PROVIDER: S-EPMC9147472 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature