Fluorescent Nanosystems for Drug Tracking and Theranostics: Recent Applications in the Ocular Field.

ABSTRACT: The greatest challenge associated with topical drug delivery for the treatment of diseases affecting the posterior segment of the eye is to overcome the poor bioavailability of the carried molecules. Nanomedicine offers the possibility to overcome obstacles related to physiological mechanisms and ocular barriers by exploiting different ocular routes. Functionalization of nanosystems by fluorescent probes could be a useful strategy to understand the pathway taken by nanocarriers into the ocular globe and to improve the desired targeting accuracy. The application of fluorescence to decorate nanocarrier surfaces or the encapsulation of fluorophore molecules makes the nanosystems a light probe useful in the landscape of diagnostics and theranostics. In this review, a state of the art on ocular

SUBMITTER: Zingale E 

PROVIDER: S-EPMC9147643 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature