The Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2.
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ABSTRACT:
SUBMITTER: Aliyari SR
PROVIDER: S-EPMC9147806 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
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The Evolutionary Dance between Innate Host Antiviral Pathways and SARS-CoV-2.
Aliyari Saba R SR Quanquin Natalie N Pernet Olivier O Zhang Shilei S Wang Lulan L Cheng Genhong G
Pathogens (Basel, Switzerland) 20220503 5
Compared to what we knew at the start of the SARS-CoV-2 global pandemic, our understanding of the interplay between the interferon signaling pathway and SARS-CoV-2 infection has dramatically increased. Innate antiviral strategies range from the direct inhibition of viral components to reprograming the host's own metabolic pathways to block viral infection. SARS-CoV-2 has also evolved to exploit diverse tactics to overcome immune barriers and successfully infect host cells. Herein, we review the ...[more]
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