Different Cutibacterium acnes Phylotypes Release Distinct Extracellular Vesicles.

ABSTRACT: Bacterial extracellular vesicles (EVs) perform various biological functions, including those that are critical to microbes. Determination of EVs composition allows for a deep understanding of their role in the bacterial community and communication among them. Cutibacterium acnes, formerly Propionibacteriumacnes, are commensal bacteria responsible for various infections, e.g., prosthesis, sarcoidosis, soft-tissue infections, and the most known but still controversial-acnes lesion. In C. acnes, three major phylotypes represented variable disease associations. Herein, for the first time, we present a comparative analysis of EVs obtained from three C. acnes phylotypes (IA1, IB, and II) to demonstrate the existence of differences in their protein and lipid com

SUBMITTER: Chudzik A 

PROVIDER: S-EPMC9147970 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature