Design and Characterization of an RF Applicator for In Vitro Tests of Electromagnetic Hyperthermia.

ABSTRACT: The evaluation of the biological effects of therapeutic hyperthermia in oncology and the precise quantification of thermal dose, when heating is coupled with radiotherapy or chemotherapy, are active fields of research. The reliable measurement of hyperthermia effects on cells and tissues requires a strong control of the delivered power and of the induced temperature rise. To this aim, we have developed a radiofrequency (RF) electromagnetic applicator operating at 434 MHz, specifically engineered for in vitro tests on 3D cell cultures. The applicator has been designed with the aid of an extensive modelling analysis, which combines electromagnetic and thermal simulations. The heating performance of the built prototype has been validated by means of temperature measurements carried out on tis

SUBMITTER: Ferrero R 

PROVIDER: S-EPMC9148047 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature