Decreased Efficiency of Between-Network Dynamics During Early Memory Consolidation With Aging.

ABSTRACT: Aging is associated with memory decline and progressive disabilities in the activities of daily living. These deficits have a significant impact on the quality of life of the aging population and lead to a tremendous burden on societies and health care systems. Understanding the mechanisms underlying aging-related memory decline is likely to inform the development of compensatory strategies promoting independence in old age. Research on aging-related memory decline has mainly focused on encoding and retrieval. However, some findings suggest that memory deficits may at least partly be due to impaired consolidation. To date, it remains elusive whether aging-related memory decline results from defective consolidation. This study examined age effects on consolidation-related neural mechanisms

SUBMITTER: Faßbender RV 

PROVIDER: S-EPMC9148994 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature