Presurgical blood metabolites and risk of postsurgical pelvic pain in young patients with endometriosis.

ABSTRACT:

Objective

To identify metabolites in presurgical blood associated with risk of persistent postsurgical pelvic pain 1 year after endometriosis surgery in adolescent and young adult patients.

Design

Prospective observational study within the Women's Health Study: From Adolescence to Adulthood, a US-based longitudinal cohort of adolescents and women enrolled from 2012-2018.

Setting

Two tertiary care hospitals.

Patient(s)

Laparoscopically confirmed endometriosis patients (n = 180) with blood collected before their endometriosis surgery. Of these, 77 patients additionally provided blood samples 5 weeks to 6 months after their surgery. We measured plasma metabolites using liquid chromatography tandem mass spectrometry, and a total of 390 known metabolites were includ

SUBMITTER: Sasamoto N 

PROVIDER: S-EPMC9149031 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature