Alternative splicing plays key roles in response to stress across different stages of fighting in the fish Betta splendens.

ABSTRACT:

Background

Aggression is an evolutionarily conserved behavior critical for animal survival. In the fish Betta splendens, across different stages of fighting interactions, fighting opponents suffer from various stressors, especially from the great demand for oxygen. Using RNA sequencing, we profiled differential alternative splicing (DAS) events in the brains of fish collected before fighting, during fighting, and after fighting to study the involvement of alternative splicing (AS) in the response to stress during the fight.

Results

We found that fighting interactions induced the greatest increase in AS in the 'during-fighting' fish, followed by that of the 'after-fighting' fish. Intron retention (IR) was the most enriched type among all the basic AS events. DAS genes were ma

SUBMITTER: Vu TD 

PROVIDER: S-EPMC9150285 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature