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An efficient route to the synthesis of novel zwitterionic pyridinium-cyanopropenides with 3-heteroaryl-substituted trimethinium salts.


ABSTRACT: In this study, eight new zwitterionic derivatives were synthesized using a simple design method from the reaction of various 2-substituted 1,3-bis(dimethylamino)-trimethinium salts with malononitrile or ethyl 2-cyanoacetate in excellent yields in the presence of triethylamine in ethanol at reflux. The molecular structures of the new compounds were confirmed by IR, UV/vis, mass, 1H, and 13C NMR spectra as well as by elemental analyses.

SUBMITTER: Samani ZR 

PROVIDER: S-EPMC9150544 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature