Abnormal Retinal Vessel Architecture in Albinism and Idiopathic Infantile Nystagmus.

ABSTRACT:

Purpose

Infantile nystagmus syndrome (INS) causes altered visual development and can be associated with abnormal retinal structure, to which vascular development of the retina is closely related. Abnormal retinal vasculature has previously been noted in albinism but not idiopathic infantile nystagmus. We compared the number and diameter of retinal vessels in participants with albinism (PWA) and idiopathic infantile nystagmus (PWIIN) with controls.

Methods

Fundus photography data from 24 PWA, 10 PWIIN, and 34 controls was analyzed using Automated Retinal Image Analyzer (ARIA) software on a field of analysis centered on the optic disc, the annulus of which extended between 4.2 mm and 8.4 mm in diameter.

Results

Compared with controls, the mean number of arterial branche

SUBMITTER: Toufeeq S 

PROVIDER: S-EPMC9150830 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature