Second-hand smoke and the risk of tuberculosis: a systematic review and a meta-analysis.

ABSTRACT: There is limited evidence and lack of consensus whether second-hand smoke (SHS) increases risk of tuberculosis (TB), which has substantial implications for unrestricted smoking indoors and TB control policies. We aimed to establish the association between SHS and the risk of acquiring and worsening of TB in non-smokers. We identified 428 articles in the initial search and 12 comparative epidemiological studies met our inclusion criteria. Exposure to SHS was found to have a higher risk of TB infection [risk ratio (RR) 1·19, 95% confidence interval (CI) 0·90-1·57] compared to non-exposure; however, this did not reach statistical significance. There was marked variability (I 2 = 74%, P = 0·0008) between studies' results, which could be explained by the differences in the diagnostic criteria u

SUBMITTER: Dogar OF 

PROVIDER: S-EPMC9150979 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature