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Asian genotypes of dengue virus 4 in Brazil.


ABSTRACT: Dengue virus, commonly transmitted by mosquitoes, causes a human disease of significant social impact and presents a serious public health problem in Brazil. This report describes the unusual emergence of DENV-4 in northern Brazil after a nearly 30-year-long absence. DENV-4 genotype I is of Asian origin and was identified in the serum of patients receiving treatment at a hospital serving the Salvador area (Brazilian state of Bahia). The identification of dengue virus serotypes through molecular and phylogenetic analysis is essential for predicting disease severity or fatal illness, principally in endemic countries such as Brazil.

SUBMITTER: Pinho AC 

PROVIDER: S-EPMC9151040 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Asian genotypes of dengue virus 4 in Brazil.

Pinho A C O AC   Sardi S I SI   Paula F L FL   Peixoto I B IB   Brandão C J CJ   Fernandez F M C FM   Campos G S GS  

Epidemiology and infection 20150223 14


Dengue virus, commonly transmitted by mosquitoes, causes a human disease of significant social impact and presents a serious public health problem in Brazil. This report describes the unusual emergence of DENV-4 in northern Brazil after a nearly 30-year-long absence. DENV-4 genotype I is of Asian origin and was identified in the serum of patients receiving treatment at a hospital serving the Salvador area (Brazilian state of Bahia). The identification of dengue virus serotypes through molecular  ...[more]

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