Norovirus genotypes implicated in two oyster-related illness outbreaks in Ireland.

ABSTRACT: We investigated norovirus (NoV) concentrations and genotypes in oyster and faecal samples associated with two separate oyster-related outbreaks of gastroenteritis in Ireland. Quantitative analysis was performed using real-time quantitative reverse transcription polymerase chain reaction and phylogenetic analysis was conducted to establish the NoV genotypes present. For both outbreaks, the NoV concentration in oysters was >1000 genome copies/g digestive tissue and multiple genotypes were identified. In faecal samples, GII.13 was the only genotype detected for outbreak 1, whereas multiple genotypes were detected in outbreak 2 following the application of cloning procedures. While various genotypes were identified in oyster samples, not all were successful in causing infection in consumers. I

SUBMITTER: Rajko-Nenow P 

PROVIDER: S-EPMC9151252 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature