The potential of bacteriophages to control Xanthomonas campestris pv. campestris at different stages of disease development.

ABSTRACT: Xanthomonas campestris pv. campestris (Xcc) is a vascular pathogen that invades the xylem of Brassica crops. Current chemical and antibiotics-based control measures for this bacterium are unsustainable and inefficient. After establishing a representative collection of Xcc strains, we isolated and characterized bacteriophages from two clades of phages to assess their potential in phage-based biocontrol. The most promising phages, FoX2 and FoX6, specifically recognize (lipo) polysaccharides, associated with the wxc gene cluster, on the surface of the bacterial cell wall. Next, we determined and optimized the applicability of FoX2 and FoX6 in an array of complementary bioassays, ranging from seed decontamination to irrigation- and spray-based applications. Here, an irrigation-based applicatio

SUBMITTER: Holtappels D 

PROVIDER: S-EPMC9151335 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature