Viral load of human bocavirus-1 in stools from children with viral diarrhoea in Paraguay.

ABSTRACT: Since their discovery, four species of human bocavirus (HBoV) have been described in patients with respiratory and gastrointestinal diseases. However, a clear causal association between HBoV-1 and gastroenteritis has not been demonstrated. In this study, we describe the detection and quantification of HBoV-1 in stools from children with acute non-bacterial gastroenteritis using quantitative polymerase chain reaction. HBoV-1 genome was detected in 10.6% of stools with frequent association with rotavirus and norovirus. The median of HBoV-1 viral load was 1.88 × 104 genome/ml, lower than previously shown in secretions of patients with respiratory infections, without any obvious association between high viral load and presence of HBoV as single agent. Thus, although HBoV-1 was frequently detec

SUBMITTER: Proenca-Modena JL 

PROVIDER: S-EPMC9151358 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature