Serum 25-hydroxyvitamin D and C-reactive protein and plasma von Willebrand concentrations in 23 dogs with chronic hepatopathies.

ABSTRACT:

Background

Serum concentrations of 25-hydroxyvitamin D (25(OH)VD) and C-reactive protein (CRP) and von Willebrand's factor (vWF) concentration correlate with histopathologic disease grade and stage in chronic inflammatory and fibrotic hepatopathies (CH) in humans.

Objectives

To evaluate serum 25(OH)VD and serum CRP concentrations and plasma vWF concentration and determine if they correlate with histopathologic and biochemical variables in dog with CH.

Animals

Twenty-three client-owned dogs with a histopathologic diagnosis of CH were prospectively enrolled.

Methods

Blood samples were collected before liver biopsy. Correlations between biomarkers and clinical pathological and histopathologic variables were evaluated using Pearson's or Spearman's test.

Results<

SUBMITTER: Ambrosini YM 

PROVIDER: S-EPMC9151486 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature