Biomarkers as predictors of recurrence of atrial fibrillation post ablation: an updated and expanded systematic review and meta-analysis.

ABSTRACT:

Background

A high proportion of patients undergoing catheter ablation (CA) for atrial fibrillation (AF) experience recurrence of arrhythmia. This meta-analysis aims to identify pre-ablation serum biomarker(s) associated with arrhythmia recurrence to improve patient selection before CA.

Methods

A systematic approach following PRISMA reporting guidelines was utilised in libraries (Pubmed/Medline, Embase, Web of Science, Scopus) and supplemented by scanning through bibliographies of articles. Biomarker levels were compared using a random-effects model and presented as odds ratio (OR). Heterogeneity was examined by meta-regression and subgroup analysis.

Results

In total, 73 studies were identified after inclusion and exclusion criteria were applied. Nine out of 22 biomark

SUBMITTER: Boyalla V 

PROVIDER: S-EPMC9151522 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature