Predictors and prognostic impact of left ventricular ejection fraction trajectories in patients with ST-segment elevation myocardial infarction.

ABSTRACT:

Background

There is little evidence on left ventricular ejection fraction (LVEF) trajectories after ST-segment elevation myocardial infarction (STEMI).

Aim

We aim to identify the LVEF trajectories after STEMI and explore their predictors and association with prognosis.

Methods

This is a retrospective, observational study of STEMI patients. The LVEF trajectories were identified by the latent class trajectory model in patients with baseline LVEF < 50%. We used logistic regression analysis to investigate the predictors for LVEF trajectories. The Cox proportional hazard model was used to assess the impact of LVEF trajectories on prognosis. The primary outcomes were cardiovascular mortality and heart failure (HF) rehospitalization.

Results

572 of 1179 patients prese

SUBMITTER: Lei Z 

PROVIDER: S-EPMC9151544 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature