The effects of positive end-expiratory pressure on cardiac function: a comparative echocardiography-conductance catheter study.

ABSTRACT:

Background

Echocardiographic parameters of diastolic function depend on cardiac loading conditions, which are altered by positive pressure ventilation. The direct effects of positive end-expiratory pressure (PEEP) on cardiac diastolic function are unknown.

Methods

Twenty-five patients without apparent diastolic dysfunction undergoing coronary angiography were ventilated noninvasively at PEEPs of 0, 5, and 10 cmH₂O (in randomized order). Echocardiographic diastolic assessment and pressure-volume-loop analysis from conductance catheters were compared. The time constant for pressure decay (τ) was modeled with exponential decay. End-diastolic and end-systolic pressure volume relationships (EDPVRs and ESPVRs, respectively) from temporary caval occlusion were analyzed w

SUBMITTER: Berger D 

PROVIDER: S-EPMC9151717 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature