Wireless implantable optical probe for continuous monitoring of oxygen saturation in flaps and organ grafts.

ABSTRACT: Continuous, real-time monitoring of perfusion after microsurgical free tissue transfer or solid organ allotransplantation procedures can facilitate early diagnosis of and intervention for anastomotic thrombosis. Current technologies including Doppler systems, cutaneous O₂-sensing probes, and fluorine magnetic resonance imaging methods are limited by their intermittent measurements, requirements for skilled personnel, indirect interfaces, and/or their tethered connections. This paper reports a wireless, miniaturized, minimally invasive near-infrared spectroscopic system designed for uninterrupted monitoring of local-tissue oxygenation. A bioresorbable barbed structure anchors the probe stably at implantation sites for a time period matched to the clinical need, with the ability f

SUBMITTER: Guo H 

PROVIDER: S-EPMC9151749 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature