A Longitudinal Study on Attenuated Structural Covariance in Patients With Somatic Symptom Disorder.

ABSTRACT:

Objective

This study was performed to investigate altered regional gray matter volume (rGMV) and structural covariance related to somatic symptom disorder (SSD) and longitudinal changes after treatment. Additionally, this study examined the relationships of structural alteration with its phenotypic subtypes.

Methods

Forty-three unmedicated patients with SSD and thirty normal controls completed psychological questionnaires and neurocognitive tests, as well as brain magnetic resonance imaging. Voxel-based morphometry and structural covariances were compared between groups and between subgroups within the SSD group. After 6 months of treatment, SSD patients were followed up for assessments.

Results

Patients with SSD exhibited attenuated structural covariances in the pall

SUBMITTER: Park HY 

PROVIDER: S-EPMC9152139 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature