Integrating data from multiple Finnish biobanks and national health-care registers for retrospective studies: Practical experiences.

ABSTRACT: Aim: This case study aimed to investigate the process of integrating resources of multiple biobanks and health-care registers, especially addressing data permit application, time schedules, co-operation of stakeholders, data exchange and data quality. Methods: We investigated the process in the context of a retrospective study: Pharmacogenomics of antithrombotic drugs (PreMed study). The study involved linking the genotype data of three Finnish biobanks (Auria Biobank, Helsinki Biobank and THL Biobank) with register data on medicine dispensations, health-care encounters and laboratory results. Results: We managed to collect a cohort of 7005 genotyped individuals, thereby achieving the statistical power requirements of the study. The data collection process took 16 mont

SUBMITTER: Lahteenmaki J 

PROVIDER: S-EPMC9152591 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature