Profile of the Nasopharyngeal Microbiota Affecting the Clinical Course in COVID-19 Patients.

ABSTRACT: While populations at risk for severe SARS-CoV-2 infections have been clearly identified, susceptibility to the infection and its clinical course remain unpredictable. As the nasopharyngeal microbiota may promote the acquisition of several respiratory infections and have an impact on the evolution of their outcome, we studied the nasopharyngeal microbiota of COVID-19 patients in association with baseline disease-related clinical features compared to that of patients tested negative. We retrospectively analyzed 120 nasopharyngeal pseudonymized samples, obtained for diagnosis, divided into groups (infected patients with a favorable outcome, asymptomatic, and deceased patients) and patients tested negative for SARS-CoV-2, by using Illumina-16S ribosomal ribonucleic acid (rRNA) sequencing and s

SUBMITTER: Tchoupou Saha OF 

PROVIDER: S-EPMC9152678 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature