Extension of cervical screening intervals with primary human papillomavirus testing: observational study of English screening pilot data.

ABSTRACT:

Objectives

To provide updated evidence about the risk of cervical intraepithelial neoplasia grade 3 or higher (CIN3+) and cervical cancer after a negative human papillomavirus (HPV) test in primary cervical screening, by age group and test assay.

Design

Observational study.

Setting

Real world data from the English HPV screening pilot's first and second rounds (2013-16, follow-up to end of 2019).

Participants

1 341 584 women.

Interventions

Cervical screening with HPV testing or liquid based cytological testing (cytology or smear tests). Women screened with cytology were referred to colposcopy after high grade cytological abnormalities or after borderline or low grade abnormalities combined with a positive HPV triage test. Women screened with HPV testing w

SUBMITTER: Rebolj M 

PROVIDER: S-EPMC9153243 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature