The role of MRI-based texture analysis to predict the severity of brain injury in neonates with perinatal asphyxia.

ABSTRACT:

Objective

To evaluate the efficacy of the MRI-based texture analysis (TA) of the basal ganglia and thalami to distinguish moderate-to-severe hypoxic-ischemic encephalopathy (HIE) from mild HIE in neonates.

Methods

This study included 68 neonates (15 with mild, 20 with moderate-to-severe HIE, and 33 control) were born at 37 gestational weeks or later and underwent MRI in first 10 days after birth. The basal ganglia and thalami were delineated for TA on the apparent diffusion coefficient (ADC) maps, T₁-, and T₂ weighted images. The basal ganglia, thalami, and the posterior limb of the internal capsule (PLIC) were also evaluated visually on diffusion-weighted imaging and T₁ weighted sequence. Receiver operating characteristi

SUBMITTER: Sarioglu FC 

PROVIDER: S-EPMC9153720 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature