SpatialExperiment: infrastructure for spatially-resolved transcriptomics data in R using Bioconductor.

ABSTRACT:

Summary

SpatialExperiment is a new data infrastructure for storing and accessing spatially-resolved transcriptomics data, implemented within the R/Bioconductor framework, which provides advantages of modularity, interoperability, standardized operations and comprehensive documentation. Here, we demonstrate the structure and user interface with examples from the 10x Genomics Visium and seqFISH platforms, and provide access to example datasets and visualization tools in the STexampleData, TENxVisiumData and ggspavis packages.

Availability and implementation

The SpatialExperiment, STexampleData, TENxVisiumData and ggspavis packages are available from Bioconductor. The package versions described in this manuscript are available in Bioconductor version 3.15 onwards.

Supplement

SUBMITTER: Righelli D 

PROVIDER: S-EPMC9154247 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature