Effect of local anaesthetic infiltration on postoperative pain after laparoscopic cholecystectomy: randomized clinical trial.

ABSTRACT:

Background

Local anaesthetic infiltration is widely used to reduce pain after laparoscopic cholecystectomy (LC). This trial evaluated the effect of depth of local anaesthetic infiltration on postoperative pain reduction after LC.

Methods

Patients undergoing elective LC between March 2018 and February 2019 were randomized into no infiltration, subcutaneous infiltration, and rectus sheath infiltration using bupivacaine. The primary outcome was 24-h postoperative cumulative morphine use, and the secondary outcomes were mean 24-h Numerical Rating Scale (NRS) for pain, and nausea, and vomiting. Subgroups were compared and multivariable analyses were performed.

Results

Out of 170 eligible patients, 162 were selected and 150 patients were analysed: 48 in the no-infiltration

SUBMITTER: Suragul W 

PROVIDER: S-EPMC9154337 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature