Endothelial Progenitor Cells in Coronary Artery Disease: From Bench to Bedside.

ABSTRACT: Endothelial progenitor cells (EPCs) are a heterogeneous group of cells present in peripheral blood at various stages of endothelial differentiation. EPCs have been extensively investigated in patients with coronary artery disease (CAD), with controversial findings both on their role in atherosclerosis progression and in the process of neointimal growth after a percutaneous coronary intervention (PCI). Despite nearly 2 decades of experimental and clinical investigations, however, the significance of EPCs in clinical practice remains unclear and poorly understood. This review provides an update on the role of EPCs in the most common clinical scenarios that are experienced by cardiologists managing patients with CAD. We here summarize the main findings on the association of EPCs with cardiova

SUBMITTER: Pelliccia F 

PROVIDER: S-EPMC9154346 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature