Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects.

ABSTRACT: Microfluidics is used to manipulate fluid flow in micro-channels to fabricate drug delivery vesicles in a uniform tunable size. Thanks to their designs, microfluidic technology provides an alternative and versatile platform over traditional formulation methods of nanoparticles. Understanding the factors that affect the formulation of nanoparticles can guide the proper selection of microfluidic design and the operating parameters aiming at producing nanoparticles with reproducible properties. This review introduces the microfluidic systems' continuous flow (single-phase) and segmented flow (multiphase) and their different mixing parameters and mechanisms. Furthermore, microfluidic approaches for efficient production of nanoparticles as surface modification, anti-fouling, and post-microfluid

SUBMITTER: Maged A 

PROVIDER: S-EPMC9154770 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature