Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial.

ABSTRACT:

Aims

Joint prevention of cardiovascular disease (CVD) and dementia could reduce the burden of both conditions. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) demonstrated a beneficial effect on cognition (primary outcome) and we assessed the effect of this lifestyle intervention on incident CVD (pre-specified secondary outcome).

Methods and results

FINGER enrolled 1259 individuals aged 60-77 years (ClinicalTrials.gov NCT01041989). They were randomized (1:1) to a 2-year multi-domain intervention with diet, physical and cognitive activity, and vascular monitoring (n = 631), or general health advice (n = 628). National registries provided data on CVD including stroke, transient ischaemic attack (TIA), or coronary heart event. Du

SUBMITTER: Lehtisalo J 

PROVIDER: S-EPMC9156384 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature