The transferability and validity of a population-level simulation model for the economic evaluation of interventions in diabetes: the MICADO model.

ABSTRACT:

Aims

Valid health economic models are essential to inform the adoption and reimbursement of therapies for diabetes mellitus. Often existing health economic models are applied in other countries and settings than those where they were developed. This practice requires assessing the transferability of a model developed from one setting to another. We evaluate the transferability of the MICADO model, developed for the Dutch 2007 setting, in two different settings using a range of adjustment steps. MICADO predicts micro- and macrovascular events at the population level.

Methods

MICADO simulation results were compared to observed events in an Italian 2000-2015 cohort (Casale Monferrato Survey [CMS]) and in a Dutch 2008-2019 (Hoorn Diabetes Care Center [DCS]) cohort after adjustin

SUBMITTER: Emamipour S 

PROVIDER: S-EPMC9156453 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature