Prognostic significance of laterality in lung neuroendocrine tumors.

ABSTRACT:

Purpose

Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts and necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage and the histopathological diagnosis, are still lacking. The current study is aimed to identify potential prognostic factors to better stratify lung NET, thus, improving patients' treatment strategy and follow-up.

Methods

A multicentric retrospective study, including 300 Lung NET, all surgically removed, from Italian and Spanish Institutions.

Results

Median age 61 years (13-86), 37.7% were males, 25.0% were AC, 42.0% were located in the lung left parenchyma, 80.3% presented a TNM stage I-II. Mitotic count was ≥2 per 10 high-power field

SUBMITTER: La Salvia A 

PROVIDER: S-EPMC9156515 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature