Identifying the Caenorhabditis elegans vulval transcriptome.

ABSTRACT: Development of the Caenorhabditis elegans vulva is a classic model of organogenesis. This system, which starts with 6 equipotent cells, encompasses diverse types of developmental event, including developmental competence, multiple signaling events to control precise and faithful patterning of three cell fates, execution and proliferation of specific cell lineages, and a series of sophisticated morphogenetic events. Early events have been subjected to extensive mutational and genetic investigations and later events to cell biological analyses. We infer the existence of dramatically changing profiles of gene expression that accompanies the observed changes in development. Yet, except from serendipitous discovery of several transcription factors expressed in dynamic patterns in vulval lineage

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC9157107 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature