Sarcopenic obesity in rheumatoid arthritis: prevalence and impact on physical functioning.

ABSTRACT:

Objective

We determined the prevalence of sarcopenic obesity in patients with RA using multiple methods and assessed associations with physical functioning.

Methods

This study evaluated data from three RA cohorts. Whole-body dual-energy absorptiometry (DXA) measures of appendicular lean mass index (ALMI, kg/m2) and fat mass index (FMI) were converted to age, sex and race-specific Z-Scores and categorized using a recently validated method and compared it to a widely-used existing method. The prevalence of body composition abnormalities in RA was compared with two reference populations. In the RA cohorts, associations between body composition and change in the HAQ and the Short Physical Performance Battery (SPPB) in follow-up were assessed using linear and logistic regression,

SUBMITTER: Baker JF 

PROVIDER: S-EPMC9157125 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature