Association of Dual Decline in Cognition and Gait Speed With Risk of Dementia in Older Adults.

ABSTRACT:

Importance

Dual decline in gait speed and cognition has been found to be associated with increased dementia risk in previous studies. However, it is unclear if risks are conferred by a decline in domain-specific cognition and gait.

Objective

To examine associations between dual decline in gait speed and cognition (ie, global, memory, processing speed, and verbal fluency) with risk of dementia.

Design, setting, and participants

This cohort study used data from older adults in Australia and the US who participated in a randomized clinical trial testing low-dose aspirin between 2010 and 2017. Eligible participants in the original trial were aged 70 years or older, or 65 years or older for US participants identifying as African American or Hispanic. Data analysis was perf

SUBMITTER: Collyer TA 

PROVIDER: S-EPMC9157262 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature