Association of High-Volume Centers With Survival Outcomes Among Patients With Nontraumatic Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis.

ABSTRACT:

Importance

Although high volume of cases of out-of-hospital cardiac arrest (OHCA) is a key feature of cardiac arrest centers, which have proven survival benefit, the role of center volume as an independent variable associated with improved outcomes is unclear.

Objective

To assess the association of high-volume centers with survival and neurological outcomes in nontraumatic OHCA.

Data sources

Medline, Embase, and the Cochrane Central Register of Controlled Trials were searched from inception to October 11, 2021, for studies including adult patients with nontraumatic OHCA who were treated at high-volume vs non-high-volume centers.

Study selection

Randomized clinical trials, nonrandomized studies of interventions, prospective cohort studies, and retrospective coho

SUBMITTER: Goh AXC 

PROVIDER: S-EPMC9157264 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature