Dataset Information

Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trial.

ABSTRACT:

Objective

To test the effectiveness of a behaviour change physiotherapy intervention to increase physical activity compared with usual rehabilitation after total hip replacement (THR) or total knee replacement (TKR).

Design

Multicentre, pragmatic, two-arm, open, randomised controlled, superiority trial.

Setting

National Health Service providers in nine English hospitals.

Participants

224 individuals aged ≥18 years, undergoing a primary THR or TKR deemed 'moderately inactive' or 'inactive'.

Intervention

Participants received either six, 30 min, weekly, group-based exercise sessions (usual care) or the same six weekly, group-based, exercise sessions each preceded by a 30 min cognitive behaviour discussion group aimed at challenging barriers to physical inactivity following surgery (experimental).

Randomisation and blinding

Initial 75 participants were randomised 1:1 before changing the allocation ratio to 2:1 (experimental:usual care). Allocation was based on minimisation, stratifying on comorbidities, operation type and hospital. There was no blinding.

Main outcome measures

Primary: University of California Los Angeles (UCLA) Activity Score at 12 months. Secondary: 6 and 12-month assessed function, pain, self-efficacy, kinesiophobia, psychological distress and quality of life.

Results

Of the 1254 participants assessed for eligibility, 224 were included (139 experimental: 85 usual care). Mean age was 68.4 years (SD: 8.7), 63% were women, 52% underwent TKR. There was no between-group difference in UCLA score (mean difference: -0.03 (95% CI -0.52 to 0.45, p=0.89)). There were no differences observed in any of the secondary outcomes at 6 or 12 months. There were no important adverse events in either group. The COVID-19 pandemic contributed to the reduced intended sample size (target 260) and reduced intervention compliance.

Conclusions

There is no evidence to suggest attending usual care physiotherapy sessions plus a group-based behaviour change intervention differs to attending usual care physiotherapy alone. As the trial could not reach its intended sample size, nor a proportion of participants receive their intended rehabilitation, this should be interpreted with caution.

Trial registration number

ISRCTN29770908.

SUBMITTER: Smith TO

PROVIDER: S-EPMC9157340 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

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Publications

Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trial.

Smith Toby O TO Parsons Scott S Ooms Alexander A Dutton Susan S Fordham Beth B Garrett Angela A Hing Caroline C Lamb Sarah S

BMJ open 20220531 5

<h4>Objective</h4>To test the effectiveness of a behaviour change physiotherapy intervention to increase physical activity compared with usual rehabilitation after total hip replacement (THR) or total knee replacement (TKR).<h4>Design</h4>Multicentre, pragmatic, two-arm, open, randomised controlled, superiority trial.<h4>Setting</h4>National Health Service providers in nine English hospitals.<h4>Participants</h4>224 individuals aged ≥18 years, undergoing a primary THR or TKR deemed 'moderately i ...[more]

PMID: 35641012

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Dataset Information

Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trial.

Objective

Design

Setting

Participants

Intervention

Randomisation and blinding

Main outcome measures

Results

Conclusions

Trial registration number

Publications

Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trial.

Similar Datasets

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