Natural marine products as antiprotozoal agents against amitochondrial parasites.
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ABSTRACT: The goal of this work is to compile and discuss molecules of marine origin reported in the scientific literature with anti-parasitic activity against Trichomonas, Giardia, and Entamoeba, parasites responsible for diseases that are major global health problems, and Microsporidial parasites as an emerging problem. The presented data correspond to metabolites with anti-parasitic activity in human beings that have been isolated by chromatographic techniques from marine sources and structurally elucidated by spectroscopic and spectrometric procedures. We also highlight some semi-synthetic derivatives that have been successful in enhancing the activity of original compounds. The biological oceanic reservoir offers the possibility to discover new biologically active molecules as lead compounds to
SUBMITTER: Estrella-Parra EA
PROVIDER: S-EPMC9157375 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
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