Presepsin for the Diagnosis of Neonatal Early-Onset Sepsis: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm infants. Timely diagnosis can be challenging owing to unspecific presentation and questionable performance of the common markers of infection. Presepsin was recently proven to be a promising biomarker for the diagnosis of EOS.

Objective

To assess presepsin accuracy for the diagnosis of EOS.

Data sources

PubMed Medline, EMBASE, Web of Science, and Google Scholar. No publication date restrictions were applied. The literature search was limited to the English language. Articles were checked for duplication.

Study selection

Inclusion criteria were studies that (1) included term or preterm newborns (defined as newborns with gestational age ≥37 weeks or <37 weeks, respectively);

SUBMITTER: Poggi C 

PROVIDER: S-EPMC9157383 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature