Association between fluid intake and extubation failure in intensive care unit patients with negative fluid balance: a retrospective observational study.

ABSTRACT:

Background

Negative fluid balance (NFB) is associated with reduced extubation failure. However, whether achieving more NFB can further improve extubation outcome has not been investigated. This study aimed to investigate whether more NFB and restricted fluid intake were associated with extubation success.

Methods

We performed a retrospective study of adult patients with mechanical ventilation (MV) admitted to Medical Information Mart for Intensive Care (MIMIC-III) from 2001 to 2012. Patients with duration of MV over 24 hours and NFB within 24 hours before extubation were included for analysis. The primary outcome was extubation failure, defined as reintubation within 72 hours after extubation. Association between fluid balance or fluid intake and extubation outcome were inve

SUBMITTER: Li T 

PROVIDER: S-EPMC9158150 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature