Intelligence outcome of pediatric intensive care unit survivors: a systematic meta-analysis and meta-regression.

ABSTRACT:

Background

Long-term morbidity after pediatric intensive care unit (PICU) admission is a growing concern. Both critical illness and accompanying PICU treatments may impact neurocognitive development as assessed by its gold standard measure; intelligence. This meta-analysis and meta-regression quantifies intelligence outcome after PICU admission and explores risk factors for poor intelligence outcome.

Methods

PubMed, Embase, CINAHL and PsycINFO were searched for relevant studies, published from database inception until September 7, 2021. Using random-effects meta-analysis, we calculated the standardized mean difference in full-scale intelligence quotient (FSIQ) between PICU survivors and controls across all included studies and additionally distinguishing between PICU subgrou

SUBMITTER: de Sonnaville ESV 

PROVIDER: S-EPMC9158152 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature