State or trait: the neurobiology of anorexia nervosa - contributions of a functional magnetic resonance imaging study.

ABSTRACT:

Background

The understanding of the cerebral neurobiology of anorexia nervosa (AN) with respect to state- versus trait-related abnormalities is limited. There is evidence of restitution of structural brain alterations with clinical remission. However, with regard to functional brain abnormalities, this issue has not yet been clarified.

Methods

We compared women with AN (n = 31), well-recovered female participants (REC) (n = 18) and non-patients (NP) (n = 27) cross-sectionally. Functional magnetic resonance imaging was performed to compare neural responses to food versus non-food images. Additionally, affective ratings were assessed.

Results

Functional responses and affective ratings did not differ between REC and NP, even when applying lenient thresholds for the compa

SUBMITTER: Goller S 

PROVIDER: S-EPMC9158182 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature