Programmed multi-level ventilation in COVID-19-related acute respiratory distress syndrome: a multi-center retrospective observational study.

ABSTRACT:

Objective

We evaluated pressure-controlled ventilation (PCV) with multiple programmed levels of positive end expiratory pressure (programmed multi-level ventilation; PMLV) in patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS).

Methods

We conducted a multicenter, retrospective study from November 2020 to February 2021. PMLV was used with PCV in all patients with intensive care admission until improvement in oxygenation (fraction of inspired oxygen [FiO₂] ≤0.50 and oxygen saturation [SpO₂] >92%). The observed outcomes were improvement of hypoxemia, length of mechanical ventilation, partial pressure of carbon dioxide (PaCO₂) stability, and adverse events.

Results

Of 188 mechanically ventil

SUBMITTER: Depta F 

PROVIDER: S-EPMC9158417 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature