Chronic Oral Anticoagulation Therapy and Prognosis of Patients Admitted to Hospital for COVID-19: Insights from the HOPE COVID-19 Registry.

ABSTRACT:

Background

Most evidence regarding anticoagulation and COVID-19 refers to the hospitalization setting, but the role of oral anticoagulation (OAC) before hospital admission has not been well explored. We compared clinical outcomes and short-term prognosis between patients with and without prior OAC therapy who were hospitalized for COVID-19.

Methods

Analysis of the whole cohort of the HOPE COVID-19 Registry which included patients discharged (deceased or alive) after hospital admission for COVID-19 in 9 countries. All-cause mortality was the primary endpoint. Study outcomes were compared after adjusting variables using propensity score matching (PSM) analyses.

Results

7698 patients were suitable for the present analysis (675 (8.8%) on OAC at admission: 427 (5.6%) on VK

SUBMITTER: Rivera-Caravaca JM 

PROVIDER: S-EPMC9158796 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature